Bioelectric Research

An Active, Robust Clinical Trial Pipeline

Accelerated wound healing + post surgical/post-traumatic/chronic intractable pain relief

Anti-microbial action + pain relief

Traumatic brain injury (TBI) reduction in cerebral edema + post-traumatic pain relief

Reduction in edema and accelerated musculoskeletal injury healing + post-traumatic pain relief

Psoriasis/neuro-dermatological skin conditions + pain relief

Opiate withdrawal symptoms treatment + extensive pain relief during withdrawal

Accelerated healing of gastrointestinal ulcers/ inflammatory bowel disease + chronic intractable pain relief

The future of ODIN 1®: Research in development

Extensive research and investigation is underway as BRC anticipates the next wave of clinical indications of use for the ODIN 1®. While treating the pain of these conditions is the currently cleared indication of use, BRC’s goal is to expand its indication of use for the treatment of these conditions:

A deeper look: the potential of ODIN 1® in wound healing



In an open wound, an electrical potential gradient is created in part by the pH gradient that occurs between the base of the wound and the skin.

This voltage potential causes a current of injury to occur which in turn attracts cells that migrate (via electrotaxis) into the wound and repair the damage. These cells consist of fibroblasts, which produce the collagen fibers used to build scar and connective tissue, macrophages and neutrophils that both initiate the inflammatory response to fight infection and ingest bacteria, and epidermal stem cells that replace missing and damaged tissue in the regeneration process.

It is hypothesized that the ODIN 1® constant reference current may help to 1) restore the current of injury, 2) generate more ATP which is required to power this process, and 3) increase nitric oxide to boost blood flow and oxygenation to the site of injury and facilitate the healing process.

Image reference: McCaig et al (2005). Controlling cell behavior electrically: current views and future potential. Physiological reviews, 85(3), 943–978.

Contact Us

For more information about these highly promising areas, please contact us.

Papers in support of clinical pipeline plans:

This device is a prescription device and may only be used under the order of a licensed provider.

Adverse Reactions

Patients may experience skin irritation beneath the electrodes applied to the skin. Patients should stop using the device and consult their physicians if they experience adverse reactions from the device.

Contraindications

Do not use this device on patients who have:

  • A cardiac or demand-type pacemaker, implanted defibrillator, or other implanted metallic electronic device, because this may cause electric shock, burns, electrical interference, or death
  • Pregnancy
  • Known neoplasm

Device should not be applied over the carotid sinus nerves, particularly in patients with known sensitivity to the carotid sinus reflex.

For complete prescribing information, please see the user's manual.